ARA-290

 ARA-290 | 10mg

ARA-290 (also known as Cibinetide or pHBSP) is a synthetic 11-amino acid peptide derived from the tissue-protective domain of erythropoietin (EPO). It is engineered to activate the innate repair receptor (IRR) while eliminating the erythropoietic (red blood cell production) effects of full-length EPO.

ARA-290 is primarily researched for its potent anti-inflammatory, neuroprotective, and tissue-repair properties. It works by modulating inflammatory pathways, promoting nerve regeneration, and supporting microvascular health without affecting hematopoiesis.

Key Research Areas:

• Neuropathy & Nerve Repair: Studied for its ability to improve neuropathic symptoms, promote corneal and peripheral nerve fiber regeneration, and support recovery in models of diabetic neuropathy and sarcoidosis-associated small fiber neuropathy.
• Anti-Inflammatory Effects: Explored for reducing chronic inflammation, inhibiting pro-inflammatory cytokines, and reprogramming tissue-damaging environments into healing states via the IRR pathway.
• Metabolic & Tissue Protection: Investigated for benefits in metabolic control, insulin sensitivity, and protection against hyperglycemia-induced damage in preclinical and clinical studies.
• Broader Regenerative Potential: Interest in applications for wound healing, organ protection, and overall tissue recovery in various stress or injury models.

For Research Use Only (RUO).