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FOX04-DRI

FOX04-DRI

$133.00
In Stock

 FOXO4-DRI | 10mg

FOXO4-DRI (also known as Proxofim) is a synthetic D-retro-inverso peptide designed as a potent senolytic agent. It targets senescent ("zombie") cells — dysfunctional cells that accumulate with age and contribute to inflammation, tissue dysfunction, and age-related decline — while sparing healthy cells.

FOXO4-DRI works by disrupting the interaction between the transcription factor FOXO4 and p53 protein in senescent cells. This interference promotes p53 nuclear exclusion, triggering selective apoptosis (programmed cell death) in these damaged cells without broadly affecting healthy tissue.

Key Research Areas for FOXO4-DRI:

  • Cellular Senescence & Anti-Aging: Studied for its ability to clear senescent cells, potentially improving tissue function, reducing inflammation, and supporting healthy aging processes in preclinical models.
  • Tissue Regeneration & Recovery: Explored for benefits in restoring physical fitness, renal function, vascular health, and other tissues affected by aging or chemotherapy in animal studies.
  • Metabolic & Hormonal Support: Investigated for effects on age-related testosterone decline, mitochondrial function, and overall vitality.
  • Inflammation & Disease Models: Potential applications in reducing senescence-associated secretory phenotype (SASP) and supporting research into osteoarthritis, vascular aging, and other age-related conditions.

For Research Use Only (RUO). 

No description available.

Additional information

Weight 0.2 lbs